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M94A0237.TXT
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1994-10-08
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Document 0237
DOCN M94A0237
TI HIV infection in recipients of blood products from donors with known
duration of infection.
DT 9412
AU Ashton LJ; Learmont J; Luo K; Wylie B; Stewart G; Kaldor JM; National
Centre in HIV Epidemiology and Clinical Research,; University of New
South Wales, Sydney, Australia.
SO Lancet. 1994 Sep 10;344(8924):718-20. Unique Identifier : AIDSLINE
MED/94359315
AB From a registry of people with transfusion-acquired HIV infection, 25
recipients were identified for whom the dates of HIV infection in the 8
corresponding donors could be established. Longer times to AIDS and to
death in recipients were independently associated (p < 0.01) with the
receipt of blood from donors who developed AIDS more than 10 years after
HIV infection, as well as with older age and fewer transfusions. Sex,
zidovudine treatment, and severity of illness at transfusion were not
significantly associated with survival.
DE Acquired Immunodeficiency Syndrome/MORTALITY/*PHYSIOPATHOLOGY
Adolescence Adult Blood Component Transfusion/*ADVERSE EFFECTS *Blood
Donors *Blood-Borne Pathogens Female Follow-Up Studies Human HIV
Infections/DRUG THERAPY/PHYSIOPATHOLOGY/*TRANSMISSION Male Middle Age
Multivariate Analysis Prognosis Support, Non-U.S. Gov't Survival
Analysis Time Factors Zidovudine/THERAPEUTIC USE JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).